中国机械工程 ›› 2010, Vol. 21 ›› Issue (7): 832-835.

• 机械基础工程 • 上一篇    下一篇

弥漫性轴索损伤实验装置的研制和应用

赵志球1;谢叻1;马延斌2;王洪财2;庄小龙1
  

  1. 1.上海交通大学国家数字化制造技术中心,上海,200030
    2.上海交通大学医学院附属第三人民医院,上海,201900
  • 出版日期:2010-04-10 发布日期:2010-04-16
  • 基金资助:
    国家自然科学基金资助项目(60873131);国家863高技术研究发展计划资助项目(2009AA01Z313) 
    National Natural Science Foundation of China(No. 60873131);
    National High-tech R&D Program of China (863 Program) (No. 2009AA01Z313)

Research and Application on Diffuse Axonal Injury Experimental Device

Zhao Zhiqiu1;Xie Le1;Ma Yanbin2;Wang Hongcai2;Zhuang Xiaolong1   

  1. 1.National Digital Manufacturing Technology Center, Shanghai Jiao Tong University, Shanghai, 200030
    2.No.3 People's Hospital Affiliated to Shanghai Jiao Tong University School of Medicine, Shanghai,201900
  • Online:2010-04-10 Published:2010-04-16
  • Supported by:
     
    National Natural Science Foundation of China(No. 60873131);
    National High-tech R&D Program of China (863 Program) (No. 2009AA01Z313)

摘要:

为研究弥漫性轴索损伤(DAI)问题,研制了一套稳定性高、重复性好且能比较真实地模拟DAI临床损伤机制的实验装置。详细阐述了实验装置的设计过程,包括驱动力的选择、联动结构设计、限位固定块的设计和传感器的选择等。最后通过大鼠实验验证了实验装置的可行性和优越性。

关键词:

Abstract:

Diffuse axonal injury (DAI), which is the most important types of brain injury, is the main cause of death, serious disability and vegetative being. In order to study the DAI, a experimental device with high stability and good reproducibility was designed, which can simulate the clinical process of the DAI injury. This paper described the design process in detail, such as the choosing of the driving force, the design of the linked structure, the design of limited block and the choice of sensors. Finally, the verification of feasibility and superiority of the device by rat experiments was done.
 

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