The mechanical and tribological properties and wear mechanism of AS41 magnesium alloy under different experimental temperatures were investigated herein. The results show that the ultimate strength and yield strength of AS41 magnesium alloy decrease with increasing of experimental temperature, whereas the elongation increases with experimental temperature increasing. In particular, the ultimate strength and yield strength prominently decrease, when the experimental temperature exceedes 150℃. With increasing the load, the frictional coefficient and wear rate display the decline and uptrend respectively under different experimental temperatures, and with increasing of sliding velocity, the frictional coefficient displayes a few change, whereas the wear rate shows an ascending trend. Under the different loads and sliding velocities, the higher the experimental temperature, the lower the frictional coefficient, but the higher the wear rate. The loads, which are the transition spots from mild wear to severe wear, brought down with the increasing of experimental temperature. The wear mechanism of AS41 magnesium alloy under a load of 50N and different experimental temperatures are presented as follows, the dominant wear mechanism in room temperature is oxidation wear and abrasive wear, the delamination wear and adhesion wear are the dominant wear mechanisms for 150℃, whereas the melting wear is the dominant wear mechanisms for the experimental temperature of 200℃ respectively.