Aiming at the factors influenced reliability allocation with uncertainty and the problems of lacking data during the early product design,a comprehensive reliability allocation method was proposed to allot the reliability index of a series of horizontal machining center based on the interval analysis and grey system theory.Considering five factors such as the complexity,failure frequency,technical level,harmfulness and maintainability that influenced allocation, combining with the expert experiences and some known informations,and using interval analysis,grey correlation analysis and entropy weight method their weights were determined.Finally,the reliability index of each subsystem was allocated according to the grey comprehensive evaluation value, and compared with the actual fault statistics results,therefore,the feasibility and accuracy of the method were verified.